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2-Bromohexadecanoic acid
CAS No. 18263-25-7
2-Bromohexadecanoic acid ( —— )
Catalog No. M21865 CAS No. 18263-25-7
2-Bromohexadecanoic acid is a PPARδ agonist. It has also been shown to inhibit fatty acid oxidation, inhibit DHHC-mediated palmitoylation, and promote glucose uptake in rat cardiac cells and the insulin-sensitive murine fibroblast line A31-IS.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
Biological Information
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Product Name2-Bromohexadecanoic acid
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NoteResearch use only, not for human use.
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Brief Description2-Bromohexadecanoic acid is a PPARδ agonist. It has also been shown to inhibit fatty acid oxidation, inhibit DHHC-mediated palmitoylation, and promote glucose uptake in rat cardiac cells and the insulin-sensitive murine fibroblast line A31-IS.
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Description2-Bromopalmitic acid (18263-25-7) inhibits protein S-palmitoylation. Blocks palmitic acid-induced increase in cAMP levels in human primary melanocytes expressing the melanocortin-1 receptor which undergoes an essential palmitoylation as a prerequisite for receptor signaling.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number18263-25-7
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Formula Weight335.32
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Molecular FormulaCH3(CH2)13CH(Br)CO2H
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCCCCCCCCCCCCC(C(=O)O)Br
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tsukamoto et al. (2013), Role of S-palmitoylation on IFITM5 for the interaction with FKBP11 in osteoblast cells; PLoS One, 8(9) e75831
2. Chen et al. (2017), Palmitoylation-dependent activation of MC1R prevents melanomagenesis; Nature, 549 399
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